Archives: Case Reports

The effects of 24 weeks of high-concentration hydrogen-rich water intake on body composition, blood lipid profiles and inflammatory biomarkers in men and women with metabolic syndrome: a randomized controlled trial Tyler W LeBaron,1,2 Ram B Singh,3 Ghizal Fatima,4 Kumar Kartikey,3 Jagdish P Sharma,3 Sergej M Ostojic,5,6 Anna Gvozdjakova,7 Branislav Kura,2 Mami Noda,8 Viliam Mojto,9 Mohammad Arif Niaz,10 doi: 10.2147/DMSO.S240122 Metabolic syndrome is associated with several medical […]

Molecular hydrogen (H2) as a potential treatment for acute and chronic fatigue Kurt Lucas,Moritz Rosch,Peter Langguth https://doi.org/10.1002/ardp.202000378 Abstract Many diseases and acute conditions can cause fatigue, which can be temporary or chronic. Acute fatigue usually develops after physical exertion or an alcoholic hangover, while microbial infections (such as the flu or COVID-19) and chronic diseases […]

Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice Ning Zhang, Changwen Deng, Xingxing Zhang, Jingxi Zhang & Chong Bai https://asthmarp.biomedcentral.com/articles/10.1186/s40733-018-0040-y Abstract Asthma is a global chronic respiratory disease that has no cure and imposes a huge burden on public health. Oxidative stress has been recognized as an important mechanism in […]

Hydrogen inhalation improves endurance in athletes Abstract In this randomized, double-blind, placebo-controlled, crossover pilot study, we evaluated the effects of 7-day inhalation of H 2 on exercise performance and serum hormonal and inflammatory profiles in a cohort of young men and women. All participants (age 22.9 ± 1.5 years; body mass index 23.4 ± 2.5 […]

Effects of taking hydrogen water in metabolic syndrome Abstract Metabolic syndrome is associated with several medical risk factors—including dyslipidemia, hyperglycemia, and obesity—which has become a global pandemic. The consequences of this condition increase the risk of cardiovascular and neurological diseases and increased mortality. Its pathophysiology is associated with redox dysregulation, excessive inflammation, and disturbances in […]

Hydrogen: A Novel Option in Human Disease Treatment Mengling Yang,1 Yinmiao Dong,1 Qingnan He,1 Ping Zhu,2 Quan Zhuang,3 Jie Shen,1 Xueyan Zhang,4 and Mingyi Zhao1 https://doi.org/10.1155/2020/8384742 Abstract H2 has shown anti-inflammatory and antioxidant capacity in multiple clinical studies, and is recommended in the latest novel coronavirus pneumonia (NCP) treatment guidelines in China. Clinical experiments have surprisingly found that H2 gas can protect the […]

Hydrogen therapy through a nasal cannula with a small flow of the gas J Clin Med Res and Elmer Press Inc doi: https://doi.org/10.14740/jocmr4323 Abstract Molecular hydrogen (H 2 ) is a biologically active gas that is widely used in the healthcare sector. In recent years, hydrogen generators that produce the gas at the point of […]

Breathing Hydrogen-Oxygen Mixture Decreases Inspiratory Effort in Patients with Tracheal Stenosis Zhou Z.-Q.a · Zhong C.-H.a · Su Z.-Q.a · Li X.-Y.b · Chen Y.a · Chen X.-B.a · Tang C.-L.a · Zhou L.-Q.a · Li S.-Y.a https://doi.org/10.1159/000492031 Abstract Background Hydrogen-oxygen (H2-O2) mixtures reduce airway resistance in patients with acute severe tracheal stenosis, but data to support the clinical use of H2-O2 are insufficient. Objective To evaluate the efficacy and safety […]

Inhalation of hydrogen gas elevates urinary 8-hydroxy-2′-deoxyguanine in Parkinson’s disease Masaaki Hirayama,1 Mikako Ito,2 Tomomi Minato,1 Asako Yoritaka,3 Tyler W. LeBaron,4,5 and Kinji Ohno, MD, PhD2,* doi: 10.4103/2045-9912.248264 Abstract Hypoemia is one of the earliest and most common symptoms in Parkinson’s disease (PD). The benefits of hydrogen water on motor deficits have been reported in PD animal models and PD patients, but […]

Effects of the long-term consumption of hydrogen-rich water on the antioxidant activity and the gut flora in female juvenile soccer players from Suzhou, China Ji-Bin Sha,1,2 Shuang-Shuang Zhang,1,6 Yi-Ming Lu,1 Wen-Jing Gong,1 Xiao-Ping Jiang,3 Jian-Jun Wang,3 Tong-Ling Qiao,4 Hong-Hong Zhang,4 Min-Qian Zhao,3 Da-Peng Wang,3 Hua Xia,4 Zhong-Wei Li,5 Jian-Liang Chen,5 Lin Zhang, PhD,6,* and Cheng-Gang Zhang, PhD1,*  doi: 10.4103/2045-9912.248263 Abstract During training and competition, a lot of physical exertion inevitably leads […]

The Effects of Hydrogen Gas Inhalation on Adverse Left Ventricular Remodeling After Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction　― First Pilot Study in Humans ― https://doi.org/10.1253/circj.CJ-17-0105 Yoshinori Katsumata, Fumiya Sano, Takayuki Abe, Tomoyoshi Tamura, Taishi Fujisawa, Yasuyuki Shiraishi, Shun Kohsaka, Ikuko Ueda, Koichiro Homma, Masaru Suzuki, Shigeo Okuda, Yuichiro Maekawa, Eiji Kobayashi, Shingo Hori, Junichi Sasaki, Keiichi Fukuda, Motoaki Sano Abstract Abstract Background: In a rat model of acute myocardial infarction […]

Efficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial Tomoyoshi Tamura, Kei Hayashida, Motoaki Sano, Shuko Onuki & Masaru Suzuki doi: 10.1186/s13063-017-2246-3. Abstract Background Hydrogen (HI) inhalation improves survival and neurological outcomes in an animal model of post-cardiac arrest syndrome (PCAS). A pilot study confirmed […]