Archives: Case Reports

A basic study on molecular hydrogen (H2) inhalation in acute cerebral ischemia patients for safety check with physiological parameters and measurement of blood H2 level Hirohisa Ono, Yoji Nishijima, Naoto Adachi, Masaki Sakamoto, Yohei Kudo, Kumi Kaneko, Atsunori Nakao & Takashi Imaoka Abstract In animal studies, the use of molecular hydrogen (H2) is considered to be quite […]

Molecular Hydrogen Consumption in the Human Body During the Inhalation of Hydrogen Gas Akito Shimouchi, Kazutoshi Nose, Tomoe Mizukami, Dock-Chil Che & Mikiyasu Shirai DOI: 10.1007/978-1-4614-7411-1_42 Abstract Breathing or ingesting hydrogen (H2) ameliorates damage caused by oxidative stress in animal models and humans. We previously reported that the entire body consumes H2 after ingesting H2-enriched water […]

Transperitoneal administration of dissolved hydrogen for peritoneal dialysis patients: a novel approach to suppress oxidative stress in the peritoneal cavity Hiroyuki Terawaki, Yoshimitsu Hayashi, Wan-Jun Zhu, Yukie Matsuyama, Tomoyoshi Terada, Shigeru Kabayama, Tsuyoshi Watanabe, Seiichi Era, Bunpei Sato & Masaaki Nakayama Medical Gas Research volume 3 https://medicalgasresearch.biomedcentral.com/articles/10.1186/2045-9912-3-14 Abstract Background Oxidative stress (OS) associated with glucose breakdown products […]

Hydrogen-Rich Water Affected Blood Alkalinity in Physically Active Men Sergej M. Ostojic & Marko D. Stojanovic |https://doi.org/10.1080/15438627.2013.852092 Abstract The potential application of an effective and safe alkalizing agent in the treatment of metabolic acidosis may be of particular interest in persons with elevated plasma acidity, such as those with exercise-induced acidosis in B. In this […]

Improved brain MRI indices in the acute brain stem infarct sites treated with hydroxyl radical scavengers, Edaravone and hydrogen, as compared to Edaravone alone. A non-controlled study Hirohisa Ono, Yoji Nishijima, Naoto Adachi, Shigekuni Tachibana, Shiroh Chitoku, Shigeo Mukaihara, Masaki Sakamoto, Yohei Kudo, Jun Nakazawa, Kumi Kaneko & Hiroshi Nawashiro Medical Gas Research volume 1 Abstract Background […]

Hydrogen drink improves exercise in physically active men and women https://www.sjss-sportsacademy.edu.rs/ Since the beginning of the Olympic Games in ancient Greece, peak physical performance has required painstaking preparation, both physically and mentally. The popular myth says that with hard training you can get any result, but the truth is much simpler – before you train […]

Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes   Kosuke Aoki, Atsunori Nakao, Takako Adachi, Yasushi Matsui & Shumpei Miyakawa Medical Gas Research  Abstract Background Muscle contractions during short periods of intense exercise can lead to oxidative stress, which may play a role in the development of […]

Psychophysiological reactions in humans during an open sea dive to 500 m with a hydrogen-helium-oxygen mixture. J Appl Physiol. 1994;76:1113-8 Abrain JH, Gardette-Chauffour MC, Martinez E, Rostain JC, Lemaire C. http://jap.physiology.org/content/76/3/1113.long Abstract Six commercial divers were examined for neurological and psychosensorimotor responses during open sea diving at 500 m with a hydrogen-helium-oxygen mixture containing 49% […]

Consumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis: an open-label pilot study Toru Ishibashi, Bunpei Sato, Mariko Rikitake, Tomoki Seo, Ryosuke Kurokawa, Yuichi Hara, Yuji Naritomi, Hiroshi Hara & Tetsuhiko Nagao Medical Gas Research Abstract Background Rheumatoid arthritis (RA) is a chronic inflammatory […]

Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. Nutr Res. 2008;28:137-43. Kajiyama S, Hasegawa G, Asano M, Hosoda H, Fukui M, Nakamura N, et al. Abstract Oxidative stress is widely recognized to be associated with a variety of disorders, including diabetes, hypertension, and atherosclerosis. […]

Effectiveness of Hydrogen Rich Water on Antioxidant Status of Subjects with Potential Metabolic Syndrome—An Open Label Pilot Study Atsunori Nakao, Yoshiya Toyoda, Prachi Sharma, Malkanthi Evans, Najla Guthrie https://doi.org/10.3164/jcbn.09-100 Abstract Metabolic syndrome is characterized by cardiometabolic risk factors, including obesity, insulin resistance, hypertension, and dyslipidemia. It is well known that oxidative stress plays an important role in the pathogenesis […]

Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies Mikako Ito, Tohru Ibi, Ko Sahashi, Masashi Ichihara, Masafumi Ito & Kinji Ohno https://medicalgasresearch.biomedcentral.com/articles/10.1186/2045-9912-1-24 Abstract Background Molecular hydrogen is important in more than 30 animal models, especially in oxidative stress-mediated diseases and inflammatory diseases. Furthermore, hydrogen effects have been reported […]