Archives: Case Reports

Hydrogen inhibits the proliferation and migration of gastric cancer cells by modulating lncRNA MALAT1/miR-124-3p/EZH2 axis https://doi.org/10.1186/s12935-020-01743-5  Abstract Background Gastric cancer is one of the most common and deadly malignancies with no effective treatment options. This study aimed to investigate the effect of hydrogen on the behavior of gastric cancer cells. Methods Gastric cancer cell lines […]

A Gallbladder Carcinoma Patient With Pseudo-Progressive Remission After Hydrogen Inhalation A Gallbladder Carcinoma Patient With Pseudo-Progressive Remission After Hydrogen Inhalation Jibing Chen,1,2 Feng Mu,1 Tianyu Lu,1 Yangyang Ma,1 Duanming Du,3 and Kecheng Xu1,2 doi: 10.2147/OTT.S227217 Abstract Background Hydrogen therapy in patients with advanced colorectal cancer has been reported to convert depleted PD-1+CD8+ T cells into PD-1 CD8+ T cells, which is associated […]

Hydrogen gas restores exhausted CD8+ T cells in patients with advanced colorectal cancer to improve prognosis https://doi.org/10.3892/or.2018.6841 Hideo Baba, Junji Akagi Introduction In cancer patients, treatment strategies, outcomes and prognosis are largely dependent on immune status and should therefore be monitored, ideally using peripheral blood markers that are easily measured non-invasively. The cytotoxic effector clusters of […]

Hydrogen: A Novel Option in Human Disease Treatment Mengling Yang, Yinmiao Dong, Qingnan He, Ping Zhu, Quan Zhuang, Jie Shen, Xueyan Zhang, Mingyi Zhao https://doi.org/10.1155/2020/8384742 Abstract H2 has shown anti-inflammatory and antioxidant capacity in multiple clinical studies and is recommended in the latest Chinese novel coronavirus pneumonia (NCP) treatment guidelines. Clinical experiments have surprisingly found […]

“Real world survey” of hydrogen-controlled cancer: a follow-up report of 82 advanced cancer patients Ji-Bing Chen1, Xiao-Feng Kong2, You-Yong Lv3, Shu-Cun Qin4, Xue-Jun Sun5, Feng Mu1, Tian-Yu Lu6, Ke-Cheng Xu6 1 Department of Cancer Rehabilitation, Fuda Cancer Hospital of Jinan University, Guangzhou, Guangdong Province, China 2 Research Center of Hydrogen Medicine, Xukecheng Health Care Studio of Guangdong Province, Guangzhou, Guangdong Province, China 3 Molecular Biology […]

Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors Abstract Background Cancer patients undergoing radiation therapy often experience fatigue and reduced quality of life (QOL). Many of the side effects of radiation therapy are thought to be related to increased oxidative stress and inflammation due to […]

Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy Abstract This study aimed to investigate the protective effect of hydrogen-rich water on liver function in colorectal cancer (CRC) patients receiving mFOLFOX6 chemotherapy. A controlled, randomized, single-blind clinical study was designed. Between June 2010 and February 2016, 152 CRC […]

Safety of Prolonged Inhalation of Hydrogen Gas in Air in Healthy Adults Cole, Alexis R. BS1; Sperotto, Francesca MD1,2,3; DiNardo, James A. MD4,5; Carlisle, Stephanie6; Rivkin, Michael J. MD7,8,9,10; Sleeper, Lynn A. ScD1,2; Kheir, John N. MD1,2 Author Information Critical Care Explorations: October 2021 – Volume 3 – Issue 10 – p e543 doi: 10.1097/CCE.0000000000000543 Abstract […]

Combating Oxidative Stress and Inflammation in COVID-19 by Molecular Hydrogen Therapy: Mechanisms and Perspectives https://doi.org/10.1155/2021/5513868 Duried Alwazeer, Tyler W. LeBaron,  Franky Fuh-Ching Liu, Xiao Yu Wu COVID-19 is a widespread global pandemic with nearly 185 million confirmed cases and about four million deaths. It is caused by an infection with the severe acute respiratory syndrome coronavirus-2 […]

Mechanism of hydrogen on cervical cancer suppression revealed by high‑throughput RNA sequencing https://doi.org/10.3892/or.2021.8092 Xiaojun Liu, Zhijun Jin, Zhifeng Wang,  Jianhong Dang, Guoqiang Chen, Lingling Li, Jing Wang, Jinghai Gao, Jing Chu Abstract Cervical cancer is considered one of the diseases with the highest mortality rate in women and limited treatment options. Hydrogen (H2) inhalation has […]

Hydrogen-rich water exerts anti-tumor effects comparable to 5-fluorouracil in a colorectal cancer xenograft model Hydrogen-rich water exerts anti-tumor effects comparable to 5-fluorouracil in a colorectal cancer xenograft model<br/ ><br/ >Asgharzadeh F, Tarnava A, Mostafapour A, Khazaei M, LeBaron TW. Hydrogen-rich water exerts anti-tumor effects comparable to 5-fluorouracil in a colorectal cancer xenograft model. World J Gastrointest Oncol 2022; 14(1): […]