Archives: Case Reports

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  • Transperitoneal administration of hydrogen suppresses peritoneal and systemic oxidative stress »

    Transperitoneal administration of dissolved hydrogen for peritoneal dialysis patients: a novel approach to suppress oxidative stress in the peritoneal cavity Hiroyuki Terawaki, Yoshimitsu Hayashi, Wan-Jun Zhu, Yukie Matsuyama, Tomoyoshi Terada, Shigeru Kabayama, Tsuyoshi Watanabe, Seiichi Era, Bunpei Sato & Masaaki Nakayama Medical Gas Research volume 3 https://medicalgasresearch.biomedcentral.com/articles/10.1186/2045-9912-3-14 Abstract Background Oxidative stress (OS) associated with glucose breakdown products […]

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  • Hydrogen-rich water as an ergogenic agent »

    Hydrogen-Rich Water Affected Blood Alkalinity in Physically Active Men Sergej M. Ostojic & Marko D. Stojanovic |https://doi.org/10.1080/15438627.2013.852092 Abstract The potential application of an effective and safe alkalizing agent in the treatment of metabolic acidosis may be of particular interest in persons with elevated plasma acidity, such as those with exercise-induced acidosis in B. In this […]

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  • Acute cerebral infarction treated with hydrogen and edaravone »

    Improved brain MRI indices in the acute brain stem infarct sites treated with hydroxyl radical scavengers, Edaravone and hydrogen, as compared to Edaravone alone. A non-controlled study Hirohisa Ono, Yoji Nishijima, Naoto Adachi, Shigekuni Tachibana, Shiroh Chitoku, Shigeo Mukaihara, Masaki Sakamoto, Yohei Kudo, Jun Nakazawa, Kumi Kaneko & Hiroshi Nawashiro Medical Gas Research volume 1 Abstract Background […]

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  • Hydrogen drink improves exercise in physically active men and women »

    Hydrogen drink improves exercise in physically active men and women https://www.sjss-sportsacademy.edu.rs/ Since the beginning of the Olympic Games in ancient Greece, peak physical performance has required painstaking preparation, both physically and mentally. The popular myth says that with hard training you can get any result, but the truth is much simpler – before you train […]

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  • Effects of drinking hydrogen-rich water on muscle fatigue in elite athletes »

    Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes   Kosuke Aoki, Atsunori Nakao, Takako Adachi, Yasushi Matsui & Shumpei Miyakawa Medical Gas Research  Abstract Background Muscle contractions during short periods of intense exercise can lead to oxidative stress, which may play a role in the development of […]

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  • Hydrogen-helium-oxygen mixture in humans during open sea diving »

    Psychophysiological reactions in humans during an open sea dive to 500 m with a hydrogen-helium-oxygen mixture. J Appl Physiol. 1994;76:1113-8 Abrain JH, Gardette-Chauffour MC, Martinez E, Rostain JC, Lemaire C. http://jap.physiology.org/content/76/3/1113.long Abstract Six commercial divers were examined for neurological and psychosensorimotor responses during open sea diving at 500 m with a hydrogen-helium-oxygen mixture containing 49% […]

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  • Molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis »

    Consumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis: an open-label pilot study Toru Ishibashi, Bunpei Sato, Mariko Rikitake, Tomoki Seo, Ryosuke Kurokawa, Yuichi Hara, Yuji Naritomi, Hiroshi Hara & Tetsuhiko Nagao Medical Gas Research Abstract Background Rheumatoid arthritis (RA) is a chronic inflammatory […]

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  • Hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes »

    Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. Nutr Res. 2008;28:137-43. Kajiyama S, Hasegawa G, Asano M, Hosoda H, Fukui M, Nakamura N, et al. Abstract Oxidative stress is widely recognized to be associated with a variety of disorders, including diabetes, hypertension, and atherosclerosis. […]

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  • Effectiveness of hydrogen-rich water in individuals with potential metabolic syndrome »

    Effectiveness of Hydrogen Rich Water on Antioxidant Status of Subjects with Potential Metabolic Syndrome—An Open Label Pilot Study Atsunori Nakao, Yoshiya Toyoda, Prachi Sharma, Malkanthi Evans, Najla Guthrie https://doi.org/10.3164/jcbn.09-100 Abstract Metabolic syndrome is characterized by cardiometabolic risk factors, including obesity, insulin resistance, hypertension, and dyslipidemia. It is well known that oxidative stress plays an important role in the pathogenesis […]

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  • Hydrogen enriched water for mitochondrial and inflammatory myopathies »

    Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies Mikako Ito, Tohru Ibi, Ko Sahashi, Masashi Ichihara, Masafumi Ito & Kinji Ohno https://medicalgasresearch.biomedcentral.com/articles/10.1186/2045-9912-1-24 Abstract Background Molecular hydrogen is important in more than 30 animal models, especially in oxidative stress-mediated diseases and inflammatory diseases. Furthermore, hydrogen effects have been reported […]

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  • Hydrogen-rich water in patients with interstitial cystitis and painful bladder syndrome »

    Effect of Supplementation With Hydrogen-rich Water in Patients With Interstitial Cystitis/Painful Bladder Syndrome Seiji Matsumoto Tomohiro Ueda Hidehiro Kakizaki DOI:https://doi.org/10.1016/j.urology.2012.10.026 Abstract Objective To study the efficacy of hydrogen-rich water in the treatment of patients with interstitial cystitis/painful bladder syndrome (IC/PBS). Methods We conducted a prospective, randomized, double-blind, placebo-controlled clinical trial of hydrogen-rich water in patients […]

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  • Addition of molecular hydrogen to hemodialysis solutions improves inflammatory responses »

    A novel bioactive haemodialysis system using dissolved dihydrogen (H2) produced by water electrolysis: a clinical trial  Masaaki Nakayama, Hirofumi Nakano, Hiromi Hamada, Noritomo Itami, Ryoichi Nakazawa, Sadayoshi Ito Nephrology Dialysis Transplantation, Volume 25, Issue 9, September 2010, Pages 3026–3033, https://doi.org/10.1093/ndt/gfq196 Abstract Background Chronic inflammation in hemodialysis (HD) patients indicates a poor prognosis. However, treatment options are limited. Hydrogen (H2) improves […]

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